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A genotype-phenotype-fitness map reveals local modularity and global pleiotropy
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
The complete genome sequence of the Staphylococcus bacteriophage Metroid
Emerging frontiers in molecular evolution
Why and how to study genetic changes with context-dependent effects
Decanalizing thinking on genetic canalization
Questioning buffering
Selection transforms the landscape of genetic variation interacting with Hsp90
Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast
Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates
The details in the distributions: How and why to study variability
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects
The ecoresponsive genome of Daphnia pulex
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
A Δ11 desaturase gene genealogy reveals two divergent allelic classes within the European corn borer
Construction of a high-resolution linkage disequilibrium map to evaluate neural tube defect risk in an Irish population
paper
A genotype-phenotype-fitness map reveals local modularity and global pleiotropy
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
The complete genome sequence of the Staphylococcus bacteriophage Metroid
Emerging frontiers in molecular evolution
Why and how to study genetic changes with context-dependent effects
Decanalizing thinking on genetic canalization
Questioning buffering
Selection transforms the landscape of genetic variation interacting with Hsp90
Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast
Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates
The details in the distributions: How and why to study variability
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects
The ecoresponsive genome of Daphnia pulex
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast
A Δ11 desaturase gene genealogy reveals two divergent allelic classes within the European corn borer
Construction of a high-resolution linkage disequilibrium map to evaluate neural tube defect risk in an Irish population
misc
Predicting the effects of mutation
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Predicting the effects of mutation
team
Katrina Liou
Anuva Banwasi
Grace Lam
Alycia Cary
Esther Cao
Naomi Jecker-Eshel
Iris Wang
Margot Bellon
Chelsea Ramjeawan
Avery Fry
Amy Diyya
Garett Maag
Daphne Newell
Rachel Eder
Sam Apodaca
Gaurav Bilolikar
Kara Schmidlin
Leandra Brettner
Yuichi Eguchi
Kerry Geiler-Samerotte
news
Our first evolution experiment has begun!
Our first paper is out!
projects
Predicting the broader impacts of drug resistant mutations
Quantifying the cost of mutations that cause protein misfolding
Learning how networks create predictable patterns of epistasis
project
Predicting the broader impacts of drug resistant mutations
Quantifying the cost of mutations that cause protein misfolding
Learning how networks create predictable patterns of epistasis
Biodesign Institute
Arizona State University
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